Welcome to CURE-Net.de

Congenital malformations arise by reason of embryonic aberration of the uro-rectal septum and pose an enormous challenge for patients and their families. Because continence is already affected at birth, lifelong physical and mental health outcomes are frequently affected by these malformations.

Malformations of the uro-rectal septum include anorectal malformations (ARM) and the exstrophy-epispadias-complex (EEC). Their overall birth prevalence has been estimated to be 1:2500 live births, leading to approximately 280 affected newborns in Germany every year.

The Network for Congenital Uro-REctal malformations (CURE-Net) is a federal program for the research of these rare diseases funded by the German BMBF (Bundesministerium für Bildung und Forschung = Federal Ministry of Education and Research). The aim is to use modern genetic and molecular biological research to
understand the causes of uro-rectal malformations and to evaluate the postoperative treatment outcome and different aftercare procedures by multicenter, clinical and psychosocial research via standardized examination procedures prospectively and by a cross-sectional study. Each concerned person and each physician who is in contact with these patients is encouraged to participate.

1st International CURE-Net Conference
Date: October 21th to 22th 2011
Venue: Heidelberg, Germany 
The flyer can be downloaded here as PDF

Network for Congenital Uro-REctal malformations (CURE-Net)
Systematic investigation of the molecular causes, clinical implications and psychosocial outcome of congenital uro-rectal malformations

News

More then 55 hospitals have ordered case report forms for newborn.

Already 450 families participate with medical and psychological data and from more than 900 families DNA was taken. We embrace the popularity, participate as well in our network!